Frontiers in Tumour Progression

Cell invasion and metastasis are the basis for most cancer-related deaths, and remain a central enigma and a crucial agenda for cancer research. It is increasingly evident that tumours developing in different organs use related but not identical strategies, likely reflective of the distinctive microenvironment they face during their ontogeny. Moreover, multiple cell types constituting the activated tumour stroma contribute to invasion and metastasis, in addition to the aberrant properties of the cancer cells. The symposium will bring together world leaders on some of the key biological and genetic mechanisms of invasion and metastasis. The main lectures will be complemented by a number of short talks selected from the submitted abstracts and a large number of posters. The organizers actively encourage presentation of unpublished work and lively discussion.

KEYNOTE SPEAKERS

Michael Karin (University of California, San Diego, USA)

Joan Massagué (Sloan-Kettering Institute, USA)

SPEAKERS

Kari Alitalo (University of Helsinki, Finland)

Hartmut Beug (Research Institute of Molecular Pathology (IMP), Austria)

Jacqueline F. Bromberg (Memorial Sloan-Kettering Cancer Center - New York, USA)

Peter Carmeliet (Katholieke Universiteit Leuven, Belgium)

Lisa Coussens (University of California, San Francisco, USA)

Frederic de Sauvage (Genentech Inc., USA)

Lee Ellis (MD Anderson Cancer Center, USA)

Theresa Guise (University of Indiana, USA)

Douglas Hanahan (ISREC, Ecole Polytechnique Fédérale de Lausanne, Switzerland)

Kent W. Hunter (Centre for Cancer Research, National Cancer Institute, National Institutes of Health, USA)

Tyler Jacks (Massachusetts Institute of Technology, USA)

Johanna Joyce (Sloan-Kettering Institute, USA)

Robert S. Kerbel (University of Toronto, Canada)

Donald McDonald (University of California, San Francisco, USA)

Stefano Piccolo (University of Padova, Italy)

Shahin Rafii (Weill Cornell Medical College, USA)

Eric Sahai (Cancer Research UK London Research Institute, UK)

Mike Stratton (Wellcome Trust Sanger Institute, UK)

Makoto Mark Taketo (Kyoto University, Japan)

Zena Werb (University of California, San Francisco, USA)

ORGANIZERS

Douglas Hanahan (ISREC, Ecole Polytechnique Fédérale de Lausanne, Switzerland)

Barbara Marte (Nature, UK)

Nicola McCarthy (Nature Reviews Cancer, UK)

Sowmya Swaminathan (Nature Cell Biology, UK)

Erwin Wagner (CNIO, Spain)

Zena Werb (University of California, San Francisco, USA)

October 24-27, 2010

Palacete de los Duques de Pastrana, Madrid, Spain

For more information and to register visit: www.nature.com/natureconferences/fitp2010