Epigenetics in Development and Disease

Recent years have witnessed rapid progress in elucidating the role of epigenetic modifications in nuclear organization and chromosome packaging, profoundly impacting our understanding of development, disease and natural variation. An increasingly diverse picture is emerging of the range of epigenetic mechanisms involved in regulating these processes, from DNA methylation and histone modification to non-coding RNAs, chromatin remodeling and interactions of higher order chromosome structures. Concurrently, rapid progress is being made in the development of technologies that facilitate the analysis of genome-wide epigenetic changes as well as the genetic and chemical means for experimentally manipulating cellular reprogramming and epigenetic modifications in stem and somatic cells. The 44th Miami Winter Symposium will bring together leaders in the field to address key aspects of the mechanisms of epigenetic regulation, cellular reprogramming, development and disease.

SYMPOSIUM AWARDEES

Distinguished Service Award:

Peter Jones (University of Southern California, USA)

Lynen Lecture:

Andrew Feinberg (Johns Hopkins School of Medicine, USA)

Lifetime Achievement Award:

Rudolf Jaenisch (Massachusetts Institute of Technology, USA)

Special Achievement Award:

Danesh Moazed (Harvard Medical School, USA)

CONFIRMED SPEAKERS

Asifa Akhtar (Max-Planck-Institute of Immunobiology, Germany)

Robin Allshire (The University of Edinburgh, UK)

Shelly Berger (University of Pennsylvania School of Medicine, USA)

Howard Cedar (Hebrew University of Jerusalem, Israel)

Job Dekker (University of Massachusetts Medical School, USA)

Manel Esteller (Bellvitge Biomedical Research Institute, Spain / University of Barcelona, Spain)

Tan Ince (University of Miami Miller School of Medicine, USA)

Tony Kouzarides (University of Cambridge, UK)

Jeannie Lee (Massachusetts General Hospital, USA)

Jason Lieb (University of North Carolina at Chapel Hill, USA)

Rolf Ohlsson (Karolinska Institutet, Sweden)

Renato Paro (ETH Zurich, Switzerland)

Wolf Reik (The Babraham Institute, UK)

Bing Ren (University of California, San Diego, USA)

Miguel Ramalho Santos (University of California, San Francisco, USA)

Paolo Sassone-Corsi (University of California, Irvine, USA)

Ramin Shiekhattar (The Wistar Institute, USA)

John Stamatoyannopoulos (University of Washington, USA)

Patrick Trojer (Constellation Pharma, USA)

Gustavo Turecki (McGill University, Canada / Douglas Mental Health Institute, Canada)

Claes Wahlestedt (Scripps Florida, USA)

Chia-Lin Wei (Genome Institute of Singapore, Singapore)

Emma Whitelaw (Queensland Institute for Medical Research, Australia)

Yi Zhang (University of North Carolina at Chapel Hill, USA)

February 6-9, 2011

JW Marriott Marquis Hotel Miami

Miami, FL, USA

For more information and to register visit:
www.nature.com/natureconferences/miami/MWS2011