The Genomics of Common Diseases

The availability of whole-genome association studies and emerging 'next-generation' sequencing technologies are redefining the genetic architecture of common diseases, revealing new susceptibility genes and offering new clues about mechanisms for a wide range of health disorders. The strategic focus of common disease genetics is progressing from the identification of susceptibility genes — with remarkable successes in the last two years — to understanding the extent to which rare and common variants explain inherited susceptibility to common diseases, to discovery of new disease mechanisms, and to pioneer and evaluate transfer of these advances through to potential clinical application.
The fourth annual conference supported by the Wellcome Trust and Nature Genetics, will aim to address the following topics, across a range of common diseases:

• Translational genetics and pharmacogenomics
• Animal models and new genomic tools
• From GWAS to mechanism
• Personal genomes, ethics and databases
• Cancer genomics
• Epigenomics and disease mechanisms
• Population and statistical genetics
• Whole genome and targeted resequencing

ORGANIZERS
Timothy Aitman (Imperial College London, UK)
David Altshuler (Broad Institute of MIT and Harvard, USA)
Myles Axton (Nature Genetics, USA)
Peter Donnelly (University of Oxford, UK)
Richard Gibbs (Baylor College of Medicine, USA)
Mary Relling (St. Jude Children's Research Hospital, USA)
KEYNOTE SPEAKERS
David Altshuler (Broad Institute of MIT and Harvard, USA)
Rick Lifton (Howard Hughes Medical Institute, Yale University, USA)
Dianna Milewicz (University of Texas Health Science Center at Houston, USA)
CONFIRMED SPEAKERS
Eric Boerwinkle (University of Texas Health Science Center at Houston, USA)
Christopher Carlson (University of Washington, USA)
Aravinda Chakravarti (Johns Hopkins University School of Medicine, USA)
Juliana Chan (The Chinese University of Hong Kong, Hong Kong)
Andrew Feinberg (Johns Hopkins University School of Medicine, USA)
Nelson Freimer (University of California, Los Angeles, USA)
Stacey Gabriel (Broad Institute of MIT and Harvard, USA)
Richard Gibbs (Baylor College of Medicine, USA)
Eric Green (National Human Genome Research Institute, USA)
Howard Jacob (Medical College of Wisconsin, USA)
Isaac Kohane (Harvard Medical School, USA)
Peter Laird (University of Southern California, USA)
Amy Maguire (Baylor College of Medicine, USA)
Mark McCarthy (University of Oxford, UK)
Rasmus Nielsen (University of California, Berkeley, USA)
Miles Parkes (University of Cambridge / Addenbrooke's Hospital, UK)
David Reich (Harvard University, USA)
Alan Shuldiner (University of Maryland School of Medicine, USA)
Matthew Stephens (University of Chicago, USA)
Jun Wang (Beijing Genomics Institute Shenzhen, China)
Hugh Watkins (University of Oxford, UK)
Robert Williams (University of Tennessee Health Science Center, USA)
Xifeng Wu (MD Anderson Cancer Center, USA)
Huda Zoghbi (Baylor College of Medicine, USA)

October 6-9, 2010
Cullen Building, Baylor College of Medicine
Houston, TX, USA

For more information and to register visit:
www.nature.com/natureconferences/gcd2010